Run the formal recovery test against the pre-registered criteria and
write the deliverable report (PLAN §6 Week 4):
- week4_recovery_test.py: evaluate hydroxyurea/L-glutamine + 5
pre-specified negative controls vs the committed criteria
- recovery_test_report.md: methodology, FAIL result with diagnosis,
top-10, lisinopril as the non-obvious candidate, limitations, v2
- known_limitations.md: L-glutamine coverage resolved, 12%-overlap
driver, recovery outcome table
Outcome: FAIL on all 3 criteria (hydroxyurea top 13%, L-glutamine
WTCS=0, 1/5 negative controls bottom-half). Root cause is signature/
assay data limitations (lost erythroid+HbF axis, 12% landmark overlap),
not the matching algorithm — reported straight per the project ethos.
Co-Authored-By: Claude Opus 4.8 (1M context) <noreply@anthropic.com>
Junior B.
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