2 Commits

Author	SHA1	Message	Date
Junior B.	72f1a49de6	Week 4: recovery test (FAIL, reported honestly) + 2-page report ... Run the formal recovery test against the pre-registered criteria and write the deliverable report (PLAN §6 Week 4): - week4_recovery_test.py: evaluate hydroxyurea/L-glutamine + 5 pre-specified negative controls vs the committed criteria - recovery_test_report.md: methodology, FAIL result with diagnosis, top-10, lisinopril as the non-obvious candidate, limitations, v2 - known_limitations.md: L-glutamine coverage resolved, 12%-overlap driver, recovery outcome table Outcome: FAIL on all 3 criteria (hydroxyurea top 13%, L-glutamine WTCS=0, 1/5 negative controls bottom-half). Root cause is signature/ assay data limitations (lost erythroid+HbF axis, 12% landmark overlap), not the matching algorithm — reported straight per the project ethos. Co-Authored-By: Claude Opus 4.8 (1M context) <noreply@anthropic.com>	2026-06-23 22:38:56 +02:00
Junior B.	b731478f5d	Scaffold Reverso MVP pipeline structure ... Set up the project skeleton per PLAN.md §4: - src/ package: identifiers, disease, drugs, scoring, provenance with pydantic schemas and confidence-tier logic (working); data-pull/compute functions stubbed per their build week - 5 starter notebooks (01-05) with PLAN-referenced steps - tests/test_scoring.py: tier-assignment tests pass; scoring reference test xfail until Week 3 - docs/: recovery_test_report, data_sources, known_limitations skeletons - pyproject.toml (requires-python >=3.11,<3.14), .gitignore, README - data/ tree preserved via .gitkeep; raw/processed/results gitignored Co-Authored-By: Claude Opus 4.8 (1M context) <noreply@anthropic.com>	2026-06-23 20:20:09 +02:00